PDB 4ifh

PDB Links
Overview

PDB Information

PDB	4IFH
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice. Deprez-Poulain, R., Hennuyer, N., Bosc, D., Liang, W.G., Enee, E., Marechal, X., Charton, J., Totobenazara, J., Berte, G., Jahklal, J., Verdelet, T., Dumont, J., Dassonneville, S., Woitrain, E., Gauriot, M., Paquet, C., Duplan, I., Hermant, P., Cantrelle, F.X., Sevin, E., Culot, M., Landry, V., Herledan, A., Piveteau, C., Lippens, G., Leroux, F., Tang, W.J., van Endert, P., Staels, B., Deprez, B. Nat Commun
Header	Hydrolase/Hydrolase Inhibitor
Released	2012-12-14
Resolution	3.290
CATH Insert Date	22 Dec, 2013

PDB Images (11)

Image of CATH 4ifh

4ifh

PDB 4ifh

Image of CATH 4ifhA

4ifhA

PDB Chain 4ifhA

Image of CATH 4ifhB

4ifhB

PDB Chain 4ifhB

Image of CATH 4ifhA01

4ifhA01

CATH Domain 4ifhA01

Image of CATH 4ifhA02

4ifhA02

CATH Domain 4ifhA02

Image of CATH 4ifhA03

4ifhA03

CATH Domain 4ifhA03

Image of CATH 4ifhA04

4ifhA04

CATH Domain 4ifhA04

Image of CATH 4ifhB01

4ifhB01

CATH Domain 4ifhB01

Image of CATH 4ifhB02

4ifhB02

CATH Domain 4ifhB02

Image of CATH 4ifhB03

4ifhB03

CATH Domain 4ifhB03

Image of CATH 4ifhB04

4ifhB04

CATH Domain 4ifhB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	23 Dec, 2013	Chopped
B	23 Dec, 2013	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4ifhA01	26 Dec, 2013	3.30.830.10	Assigned
4ifhA02	26 Dec, 2013	3.30.830.10	Assigned
4ifhA03	26 Dec, 2013	3.30.830.10	Assigned
4ifhA04	26 Dec, 2013	3.30.830.10	Assigned
4ifhB01	26 Dec, 2013	3.30.830.10	Assigned
4ifhB02	26 Dec, 2013	3.30.830.10	Assigned
4ifhB03	26 Dec, 2013	3.30.830.10	Assigned
4ifhB04	26 Dec, 2013	3.30.830.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme