PDB Information

PDB4IEM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes.
Tsutakawa, S.E., Shin, D.S., Mol, C.D., Izumi, T., Arvai, A.S., Mantha, A.K., Szczesny, B., Ivanov, I.N., Hosfield, D.J., Maiti, B., Pique, M.E., Frankel, K.A., Hitomi, K., Cunningham, R.P., Mitra, S., Tainer, J.A.
J.Biol.Chem.
HeaderHydrolase, Lyase/Dna
Released2012-12-13
Resolution2.390
CATH Insert Date27 Jan, 2013

PDB Images (21)

PDB Prints

PDB Chains (16)

Chain ID Date inserted into CATH CATH Status
A 28 Jan, 2013 Chopped
B 28 Jan, 2013 Chopped
C 28 Jan, 2013 Chopped
D 28 Jan, 2013 Chopped
E 28 Jan, 2013 Rejected
F 28 Jan, 2013 Rejected
G 28 Jan, 2013 Rejected
H 28 Jan, 2013 Rejected
I 28 Jan, 2013 Rejected
J 28 Jan, 2013 Rejected
K 28 Jan, 2013 Rejected
L 28 Jan, 2013 Rejected
M 28 Jan, 2013 Rejected
N 28 Jan, 2013 Rejected
O 28 Jan, 2013 Rejected
P 28 Jan, 2013 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4iemA00 08 Feb, 2013 3.60.10.10 Assigned
4iemB00 08 Feb, 2013 3.60.10.10 Assigned
4iemC00 08 Feb, 2013 3.60.10.10 Assigned
4iemD00 08 Feb, 2013 3.60.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P27695 APEX1_HUMAN Homo sapiens DNA-(apurinic or apyrimidinic site) lyase
P27695 APEX1_HUMAN Homo sapiens DNA-(apurinic or apyrimidinic site) lyase
P27695 APEX1_HUMAN Homo sapiens DNA-(apurinic or apyrimidinic site) lyase
P27695 APEX1_HUMAN Homo sapiens DNA-(apurinic or apyrimidinic site) lyase