PDB Information

PDB4HB3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Sun, Q., Carrasco, Y.P., Hu, Y., Guo, X., Mirzaei, H., Macmillan, J., Chook, Y.M.
Proc.Natl.Acad.Sci.USA
HeaderProtein Transport/Antibiotic
Released2012-09-27
Resolution2.800
CATH Insert Date20 Jan, 2013

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 21 Jan, 2013 Chopped
B 21 Jan, 2013 Chopped
C 21 Jan, 2013 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4hb3A00 25 Apr, 2013 3.40.50.300 Assigned
4hb3B00 24 Jan, 2013 2.30.29.30 Assigned
4hb3C00 06 Sep, 2013 Holding pen

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P30822 XPO1_YEAST Saccharomyces cerevisiae S288C Exportin-1
P62826 RAN_HUMAN Homo sapiens GTP-binding nuclear protein Ran
P41920 YRB1_YEAST Saccharomyces cerevisiae S288C Ran-specific GTPase-activating protein 1