×
Network disruptions
We have been experiencing disruptions on our local network which has affected the stability of these web pages.
We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.
PDB Information
| PDB | 4HAW |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation |
Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Sun, Q., Carrasco, Y.P., Hu, Y., Guo, X., Mirzaei, H., Macmillan, J., Chook, Y.M.
Proc.Natl.Acad.Sci.USA
|
| Header | Protein Transport/Antibiotic |
| Released | 2012-09-27 |
| Resolution | 1.900 |
| CATH Insert Date | 20 Jan, 2013 |
PDB Images (7)
4hawA00
CATH Domain 4hawA00
4hawB00
CATH Domain 4hawB00
4hawC00
CATH Domain 4hawC00
PDB Chains (3)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 21 Jan, 2013 | Chopped
|
| B | 21 Jan, 2013 | Chopped
|
| C | 21 Jan, 2013 | Chopped
|
CATH Domains (3)
UniProtKB Entries (3)
| Accession |
Gene ID |
Taxon |
Description |
| P41920 |
YRB1_YEAST |
Saccharomyces cerevisiae S288C |
Ran-specific GTPase-activating protein 1 |
| P30822 |
XPO1_YEAST |
Saccharomyces cerevisiae S288C |
Exportin-1 |
| P62826 |
RAN_HUMAN |
Homo sapiens |
GTP-binding nuclear protein Ran |