PDB Information

PDB4H5C
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure.
Park, J., Lin, Y.S., De Schutter, J.W., Tsantrizos, Y.S., Berghuis, A.M.
Bmc Struct.Biol.
HeaderTransferase/Transferase Inhibitor
Released2012-09-18
Resolution2.020
CATH Insert Date30 Dec, 2012

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
F 31 Dec, 2012 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4h5cF00 03 Jan, 2013 1.10.600.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P14324 FPPS_HUMAN Homo sapiens Farnesyl pyrophosphate synthase