PDB Information

PDB4GW6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Primary Citation
The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors.
Feng, L., Sharma, A., Slaughter, A., Jena, N., Koh, Y., Shkriabai, N., Larue, R.C., Patel, P.A., Mitsuya, H., Kessl, J.J., Engelman, A., Fuchs, J.R., Kvaratskhelia, M.
J.Biol.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-08-31
Resolution2.650
CATH Insert Date07 Jul, 2013

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4gw6A00 09 Aug, 2013 3.30.420.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P12497 POL_HV1N5 Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) Gag-Pol polyprotein