PDB 4gsy

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Overview

PDB Information

PDB	4GSY
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Staphylococcus aureus subsp. aureus
Primary Citation	Discovery of Selective and Potent Inhibitors of Gram-Positive Bacterial Thymidylate Kinase (TMK). Martinez-Botella, G., Breen, J.N., Duffy, J.E., Dumas, J., Geng, B., Gowers, I.K., Green, O.M., Guler, S., Hentemann, M.F., Hernandez-Juan, F.A., Joseph-McCarthy, D., Kawatkar, S., Larsen, N.A., Lazari, O., Loch, J.T., Macritchie, J.A., McKenzie, A.R., Newman, J.V., Olivier, N.B., Otterson, L.G., Owens, A.P., Read, J., Sheppard, D.W., Keating, T.A. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2012-08-28
Resolution	1.710
CATH Insert Date	04 Nov, 2012

PDB Images (5)

Image of CATH 4gsy

4gsy

PDB 4gsy

Image of CATH 4gsyA

4gsyA

PDB Chain 4gsyA

Image of CATH 4gsyB

4gsyB

PDB Chain 4gsyB

Image of CATH 4gsyA00

4gsyA00

CATH Domain 4gsyA00

Image of CATH 4gsyB00

4gsyB00

CATH Domain 4gsyB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped
B	05 Nov, 2012	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4gsyA00	10 Nov, 2012	3.40.50.300	Assigned
4gsyB00	10 Nov, 2012	3.40.50.300	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q6GJI9	KTHY_STAAR	Staphylococcus aureus subsp. aureus MRSA252	Thymidylate kinase
Q6GJI9	KTHY_STAAR	Staphylococcus aureus subsp. aureus MRSA252	Thymidylate kinase