PDB 4gsc

PDB Links
Overview

PDB Information

PDB	4GSC
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	Homo sapiens
Primary Citation	Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis. Charton, J., Gauriot, M., Guo, Q., Hennuyer, N., Marechal, X., Dumont, J., Hamdane, M., Pottiez, V., Landry, V., Sperandio, O., Flipo, M., Buee, L., Staels, B., Leroux, F., Tang, W.J., Deprez, B., Deprez-Poulain, R. Eur.J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2012-08-27
Resolution	2.810
CATH Insert Date	15 Sep, 2013

PDB Images (11)

Image of CATH 4gsc

4gsc

PDB 4gsc

Image of CATH 4gscA

4gscA

PDB Chain 4gscA

Image of CATH 4gscB

4gscB

PDB Chain 4gscB

Image of CATH 4gscA01

4gscA01

CATH Domain 4gscA01

Image of CATH 4gscA02

4gscA02

CATH Domain 4gscA02

Image of CATH 4gscA03

4gscA03

CATH Domain 4gscA03

Image of CATH 4gscA04

4gscA04

CATH Domain 4gscA04

Image of CATH 4gscB01

4gscB01

CATH Domain 4gscB01

Image of CATH 4gscB02

4gscB02

CATH Domain 4gscB02

Image of CATH 4gscB03

4gscB03

CATH Domain 4gscB03

Image of CATH 4gscB04

4gscB04

CATH Domain 4gscB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	16 Sep, 2013	Chopped
B	16 Sep, 2013	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4gscA01	30 Oct, 2013	3.30.830.10	Assigned
4gscA02	30 Oct, 2013	3.30.830.10	Assigned
4gscA03	30 Oct, 2013	3.30.830.10	Assigned
4gscA04	30 Oct, 2013	3.30.830.10	Assigned
4gscB01	30 Oct, 2013	3.30.830.10	Assigned
4gscB02	30 Oct, 2013	3.30.830.10	Assigned
4gscB03	30 Oct, 2013	3.30.830.10	Assigned
4gscB04	30 Oct, 2013	3.30.830.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme