PDB 4gmx

PDB Links
Overview

PDB Information

PDB	4GMX
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia. Lapalombella, R., Sun, Q., Williams, K., Tangeman, L., Jha, S., Zhong, Y., Goettl, V., Mahoney, E., Berglund, C., Gupta, S., Farmer, A., Mani, R., Johnson, A.J., Lucas, D., Mo, X., Daelemans, D., Sandanayaka, V., Shechter, S., McCauley, D., Shacham, S., Kauffman, M., Chook, Y.M., Byrd, J.C. Blood
Header	Protein Transport/Inhibitor
Released	2012-08-16
Resolution	2.100
CATH Insert Date	04 Nov, 2012

PDB Images (7)

Image of CATH 4gmx

4gmx

PDB 4gmx

Image of CATH 4gmxA

4gmxA

PDB Chain 4gmxA

Image of CATH 4gmxB

4gmxB

PDB Chain 4gmxB

Image of CATH 4gmxC

4gmxC

PDB Chain 4gmxC

Image of CATH 4gmxA00

4gmxA00

CATH Domain 4gmxA00

Image of CATH 4gmxB00

4gmxB00

CATH Domain 4gmxB00

Image of CATH 4gmxC00

4gmxC00

CATH Domain 4gmxC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped
B	05 Nov, 2012	Chopped
C	05 Nov, 2012	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4gmxA00	25 Apr, 2013	3.40.50.300	Assigned
4gmxB00	10 Nov, 2012	2.30.29.30	Assigned
4gmxC00	28 Aug, 2013		Holding pen

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P30822	XPO1_YEAST	Saccharomyces cerevisiae S288C	Exportin-1
P62826	RAN_HUMAN	Homo sapiens	GTP-binding nuclear protein Ran
P41920	YRB1_YEAST	Saccharomyces cerevisiae S288C	Ran-specific GTPase-activating protein 1