PDB 4gmb

PDB Information

PDB4GMB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction.
Karatas, H., Li, Y., Liu, L., Ji, J., Lee, S., Chen, Y., Yang, J., Huang, L., Bernard, D., Xu, J., Townsend, E.C., Cao, F., Ran, X., Li, X., Wen, B., Sun, D., Stuckey, J.A., Lei, M., Dou, Y., Wang, S.
J. Med. Chem.
HeaderTranscription/Transcription Inhibitor
Released2012-08-15
Resolution2.780
CATH Insert Date23 Feb, 2014

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Feb, 2014 Chopped
E 24 Feb, 2014 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4gmbA00 07 Mar, 2014 2.130.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5