PDB 4gm3

PDB Information

PDB4GM3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction.
Karatas, H., Townsend, E.C., Cao, F., Chen, Y., Bernard, D., Liu, L., Lei, M., Dou, Y., Wang, S.
J.Am.Chem.Soc.
HeaderTranscription/Transcription Inhibitor
Released2012-08-15
Resolution3.390
CATH Insert Date18 Aug, 2013

PDB Images (25)

PDB Prints

PDB Chains (16)

Chain ID Date inserted into CATH CATH Status
A 19 Aug, 2013 Chopped
B 19 Aug, 2013 Chopped
C 19 Aug, 2013 Chopped
D 19 Aug, 2013 Chopped
E 19 Aug, 2013 Chopped
F 19 Aug, 2013 Chopped
G 19 Aug, 2013 Chopped
H 19 Aug, 2013 Chopped
I 19 Aug, 2013 Rejected
J 19 Aug, 2013 Rejected
K 19 Aug, 2013 Rejected
L 19 Aug, 2013 Rejected
M 19 Aug, 2013 Rejected
N 19 Aug, 2013 Rejected
O 19 Aug, 2013 Rejected
P 19 Aug, 2013 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4gm3A00 27 Aug, 2013 2.130.10.10 Assigned
4gm3B00 27 Aug, 2013 2.130.10.10 Assigned
4gm3C00 27 Aug, 2013 2.130.10.10 Assigned
4gm3D00 27 Aug, 2013 2.130.10.10 Assigned
4gm3E00 27 Aug, 2013 2.130.10.10 Assigned
4gm3F00 27 Aug, 2013 2.130.10.10 Assigned
4gm3G00 27 Aug, 2013 2.130.10.10 Assigned
4gm3H00 27 Aug, 2013 2.130.10.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5