PDB 4g5s

PDB Information

PDB4G5S
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
To be Published
HeaderCell Cycle/Signaling Protein
Released2012-07-18
Resolution3.620
CATH Insert Date04 Nov, 2012

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped
C 05 Nov, 2012 Chopped
D 05 Nov, 2012 Chopped
E 05 Nov, 2012 Rejected
F 05 Nov, 2012 Rejected
G 05 Nov, 2012 Rejected
Z 05 Nov, 2012 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4g5sA01 08 Feb, 2013 3.40.50.300 Assigned
4g5sA02 08 Feb, 2013 1.10.400.10 Assigned
4g5sB01 08 Feb, 2013 3.40.50.300 Assigned
4g5sB02 08 Feb, 2013 1.10.400.10 Assigned
4g5sC01 08 Feb, 2013 3.40.50.300 Assigned
4g5sC02 08 Feb, 2013 1.10.400.10 Assigned
4g5sD01 08 Feb, 2013 3.40.50.300 Assigned
4g5sD02 08 Feb, 2013 1.10.400.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q8VDU0 GPSM2_MOUSE Mus musculus G-protein-signaling modulator 2
P08754 GNAI3_HUMAN Homo sapiens Guanine nucleotide-binding protein G(k) subunit alpha
Q8VDU0 GPSM2_MOUSE Mus musculus G-protein-signaling modulator 2
Q8VDU0 GPSM2_MOUSE Mus musculus G-protein-signaling modulator 2
P08754 GNAI3_HUMAN Homo sapiens Guanine nucleotide-binding protein G(k) subunit alpha
P08754 GNAI3_HUMAN Homo sapiens Guanine nucleotide-binding protein G(k) subunit alpha
P08754 GNAI3_HUMAN Homo sapiens Guanine nucleotide-binding protein G(k) subunit alpha
Q8VDU0 GPSM2_MOUSE Mus musculus G-protein-signaling modulator 2