PDB Information

PDB4FOX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMycobacterium tuberculosis
Primary Citation
Crystal structure of binary and ternary complexes of thymidylate synthase (ThyA) from Mycobacterium tuberculosis: Insights into the selectivity and mode of inhibition
Reddy, M.C.M., Bruning, J.B., Sacchettini, J.C., Harshbarger, W.
To be Published
HeaderTransferase
Released2012-06-21
Resolution2.300
CATH Insert Date01 Sep, 2013

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 02 Sep, 2013 Chopped
B 02 Sep, 2013 Chopped
C 02 Sep, 2013 Chopped
D 02 Sep, 2013 Chopped
E 02 Sep, 2013 Chopped
F 02 Sep, 2013 Chopped
G 02 Sep, 2013 Chopped
H 02 Sep, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4foxA00 04 Sep, 2013 3.30.572.10 Assigned
4foxB00 04 Sep, 2013 3.30.572.10 Assigned
4foxC00 04 Sep, 2013 3.30.572.10 Assigned
4foxD00 04 Sep, 2013 3.30.572.10 Assigned
4foxE00 04 Sep, 2013 3.30.572.10 Assigned
4foxF00 04 Sep, 2013 3.30.572.10 Assigned
4foxG00 04 Sep, 2013 3.30.572.10 Assigned
4foxH00 04 Sep, 2013 3.30.572.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P9WFR9 TYSY_MYCTU Mycobacterium tuberculosis H37Rv Thymidylate synthase ThyA
P9WFR9 TYSY_MYCTU Mycobacterium tuberculosis H37Rv Thymidylate synthase ThyA
P9WFR9 TYSY_MYCTU Mycobacterium tuberculosis H37Rv Thymidylate synthase ThyA
P9WFR9 TYSY_MYCTU Mycobacterium tuberculosis H37Rv Thymidylate synthase ThyA
P9WFR9 TYSY_MYCTU Mycobacterium tuberculosis H37Rv Thymidylate synthase ThyA
P9WFR9 TYSY_MYCTU Mycobacterium tuberculosis H37Rv Thymidylate synthase ThyA
P9WFR9 TYSY_MYCTU Mycobacterium tuberculosis H37Rv Thymidylate synthase ThyA
P9WFR9 TYSY_MYCTU Mycobacterium tuberculosis H37Rv Thymidylate synthase ThyA