PDB 4fhk

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PDB Links
Overview

PDB Information

PDB	4FHK
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors. Peterson, E.A., Boezio, A.A., Andrews, P.S., Boezio, C.M., Bush, T.L., Cheng, A.C., Choquette, D., Coats, J.R., Colletti, A.E., Copeland, K.W., DuPont, M., Graceffa, R., Grubinska, B., Kim, J.L., Lewis, R.T., Liu, J., Mullady, E.L., Potashman, M.H., Romero, K., Shaffer, P.L., Stanton, M.K., Stellwagen, J.C., Teffera, Y., Yi, S., Cai, T., La, D.S. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2012-06-06
Resolution	3.000
CATH Insert Date	07 Jul, 2013

PDB Images (7)

Image of CATH 4fhk

4fhk

PDB 4fhk

Image of CATH 4fhkA

4fhkA

PDB Chain 4fhkA

Image of CATH 4fhkA01

4fhkA01

CATH Domain 4fhkA01

Image of CATH 4fhkA02

4fhkA02

CATH Domain 4fhkA02

Image of CATH 4fhkA03

4fhkA03

CATH Domain 4fhkA03

Image of CATH 4fhkA04

4fhkA04

CATH Domain 4fhkA04

Image of CATH 4fhkA05

4fhkA05

CATH Domain 4fhkA05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	08 Jul, 2013	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4fhkA01	09 Aug, 2013	3.10.20.90	Assigned
4fhkA02	09 Aug, 2013	2.60.40.150	Assigned
4fhkA03	09 Aug, 2013	1.25.40.70	Assigned
4fhkA04	09 Aug, 2013	3.30.1010.10	Assigned
4fhkA05	09 Aug, 2013	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform