PDB 4fad

PDB Links
Overview

PDB Information

PDB	4FAD
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kalpha and mTOR Le, P.T., Cheng, H., Ninkovic, S., Plewe, M., Huang, X., Wang, H., Bagrodia, S., Sun, S., Knighton, D.R., LaFleur Rogers, C.M., Pannifer, A., Greasley, S., Dalvie, D., Zhang, E. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2012-05-22
Resolution	2.700
CATH Insert Date	07 Jul, 2013

PDB Images (7)

Image of CATH 4fad

4fad

PDB 4fad

Image of CATH 4fadA

4fadA

PDB Chain 4fadA

Image of CATH 4fadA01

4fadA01

CATH Domain 4fadA01

Image of CATH 4fadA02

4fadA02

CATH Domain 4fadA02

Image of CATH 4fadA03

4fadA03

CATH Domain 4fadA03

Image of CATH 4fadA04

4fadA04

CATH Domain 4fadA04

Image of CATH 4fadA05

4fadA05

CATH Domain 4fadA05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	08 Jul, 2013	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4fadA01	09 Aug, 2013	3.10.20.90	Assigned
4fadA02	09 Aug, 2013	2.60.40.150	Assigned
4fadA03	09 Aug, 2013	1.25.40.70	Assigned
4fadA04	09 Aug, 2013	3.30.1010.10	Assigned
4fadA05	09 Aug, 2013	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform