PDB 4eu2

PDB Links
Overview

PDB Information

PDB	4EU2
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding. Kikuchi, J., Shibayama, N., Yamada, S., Wada, T., Nobuyoshi, M., Izumi, T., Akutsu, M., Kano, Y., Sugiyama, K., Ohki, M., Park, S.Y., Furukawa, Y. Plos One
Header	Hydrolase/Hydrolase Inhibitor
Released	2012-04-25
Resolution	2.510
CATH Insert Date	07 Jul, 2013

PDB Images (57)

4eu2

PDB 4eu2

4eu21

PDB Chain 4eu21

4eu22

PDB Chain 4eu22

4eu2A

PDB Chain 4eu2A

4eu2B

PDB Chain 4eu2B

4eu2C

PDB Chain 4eu2C

4eu2D

PDB Chain 4eu2D

4eu2E

PDB Chain 4eu2E

4eu2F

PDB Chain 4eu2F

4eu2G

PDB Chain 4eu2G

4eu2H

PDB Chain 4eu2H

4eu2I

PDB Chain 4eu2I

4eu2J

PDB Chain 4eu2J

4eu2K

PDB Chain 4eu2K

4eu2L

PDB Chain 4eu2L

4eu2M

PDB Chain 4eu2M

4eu2N

PDB Chain 4eu2N

4eu2O

PDB Chain 4eu2O

4eu2P

PDB Chain 4eu2P

4eu2Q

PDB Chain 4eu2Q

4eu2R

PDB Chain 4eu2R

4eu2S

PDB Chain 4eu2S

4eu2T

PDB Chain 4eu2T

4eu2U

PDB Chain 4eu2U

4eu2V

PDB Chain 4eu2V

4eu2W

PDB Chain 4eu2W

4eu2X

PDB Chain 4eu2X

4eu2Y

PDB Chain 4eu2Y

4eu2Z

PDB Chain 4eu2Z

4eu2100

CATH Domain 4eu2100

4eu2200

CATH Domain 4eu2200

4eu2A00

CATH Domain 4eu2A00

4eu2B00

CATH Domain 4eu2B00

4eu2C00

CATH Domain 4eu2C00

4eu2D00

CATH Domain 4eu2D00

4eu2E00

CATH Domain 4eu2E00

4eu2F00

CATH Domain 4eu2F00

4eu2G00

CATH Domain 4eu2G00

4eu2H00

CATH Domain 4eu2H00

4eu2I00

CATH Domain 4eu2I00

4eu2J00

CATH Domain 4eu2J00

4eu2K00

CATH Domain 4eu2K00

4eu2L00

CATH Domain 4eu2L00

4eu2M00

CATH Domain 4eu2M00

4eu2N00

CATH Domain 4eu2N00

4eu2O00

CATH Domain 4eu2O00

4eu2P00

CATH Domain 4eu2P00

4eu2Q00

CATH Domain 4eu2Q00

4eu2R00

CATH Domain 4eu2R00

4eu2S00

CATH Domain 4eu2S00

4eu2T00

CATH Domain 4eu2T00

4eu2U00

CATH Domain 4eu2U00

4eu2V00

CATH Domain 4eu2V00

4eu2W00

CATH Domain 4eu2W00

4eu2X00

CATH Domain 4eu2X00

4eu2Y00

CATH Domain 4eu2Y00

4eu2Z00

CATH Domain 4eu2Z00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
1	08 Jul, 2013	Chopped
2	08 Jul, 2013	Chopped
A	08 Jul, 2013	Chopped
B	08 Jul, 2013	Chopped
C	08 Jul, 2013	Chopped
D	08 Jul, 2013	Chopped
E	08 Jul, 2013	Chopped
F	08 Jul, 2013	Chopped
G	08 Jul, 2013	Chopped
H	08 Jul, 2013	Chopped
I	08 Jul, 2013	Chopped
J	08 Jul, 2013	Chopped
K	08 Jul, 2013	Chopped
L	08 Jul, 2013	Chopped
M	08 Jul, 2013	Chopped
N	08 Jul, 2013	Chopped
O	08 Jul, 2013	Chopped
P	08 Jul, 2013	Chopped
Q	08 Jul, 2013	Chopped
R	08 Jul, 2013	Chopped
S	08 Jul, 2013	Chopped
T	08 Jul, 2013	Chopped
U	08 Jul, 2013	Chopped
V	08 Jul, 2013	Chopped
W	08 Jul, 2013	Chopped
X	08 Jul, 2013	Chopped
Y	08 Jul, 2013	Chopped
Z	08 Jul, 2013	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4eu2100	09 Aug, 2013	3.60.20.10	Assigned
4eu2200	09 Aug, 2013	3.60.20.10	Assigned
4eu2A00	09 Aug, 2013	3.60.20.10	Assigned
4eu2B00	09 Aug, 2013	3.60.20.10	Assigned
4eu2C00	09 Aug, 2013	3.60.20.10	Assigned
4eu2D00	09 Aug, 2013	3.60.20.10	Assigned
4eu2E00	09 Aug, 2013	3.60.20.10	Assigned
4eu2F00	09 Aug, 2013	3.60.20.10	Assigned
4eu2G00	09 Aug, 2013	3.60.20.10	Assigned
4eu2H00	09 Aug, 2013	3.60.20.10	Assigned
4eu2I00	09 Aug, 2013	3.60.20.10	Assigned
4eu2J00	09 Aug, 2013	3.60.20.10	Assigned
4eu2K00	09 Aug, 2013	3.60.20.10	Assigned
4eu2L00	09 Aug, 2013	3.60.20.10	Assigned
4eu2M00	08 Aug, 2013	3.60.20.10	Assigned
4eu2N00	08 Aug, 2013	3.60.20.10	Assigned
4eu2O00	08 Aug, 2013	3.60.20.10	Assigned
4eu2P00	08 Aug, 2013	3.60.20.10	Assigned
4eu2Q00	08 Aug, 2013	3.60.20.10	Assigned
4eu2R00	08 Aug, 2013	3.60.20.10	Assigned
4eu2S00	08 Aug, 2013	3.60.20.10	Assigned
4eu2T00	08 Aug, 2013	3.60.20.10	Assigned
4eu2U00	08 Aug, 2013	3.60.20.10	Assigned
4eu2V00	08 Aug, 2013	3.60.20.10	Assigned
4eu2W00	08 Aug, 2013	3.60.20.10	Assigned
4eu2X00	08 Aug, 2013	3.60.20.10	Assigned
4eu2Y00	08 Aug, 2013	3.60.20.10	Assigned
4eu2Z00	08 Aug, 2013	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1