PDB 4edx

PDB Information

PDB4EDX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes.
La Porte, S.L., Eigenbrot, C., Ultsch, M., Ho, W.H., Foletti, D., Forgie, A., Lindquist, K.C., Shelton, D.L., Pons, J.
MAbs
HeaderImmune System
Released2012-03-27
Resolution2.500
CATH Insert Date06 Apr, 2014

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2014 Chopped
B 07 Apr, 2014 Chopped
H 07 Apr, 2014 Chopped
L 07 Apr, 2014 Chopped
V 07 Apr, 2014 Chopped
W 07 Apr, 2014 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
4edxA01 17 Apr, 2014 2.60.40.10 Assigned
4edxA02 17 Apr, 2014 2.60.40.10 Assigned
4edxB01 25 Apr, 2014 2.60.40.10 Assigned
4edxB02 25 Apr, 2014 2.60.40.10 Assigned
4edxH01 25 Apr, 2014 2.60.40.10 Assigned
4edxH02 25 Apr, 2014 2.60.40.10 Assigned
4edxL01 25 Apr, 2014 2.60.40.10 Assigned
4edxL02 25 Apr, 2014 2.60.40.10 Assigned
4edxV00 25 Apr, 2014 2.10.90.10 Assigned
4edxW00 25 Apr, 2014 2.10.90.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P01138 NGF_HUMAN Homo sapiens Beta-nerve growth factor
P01138 NGF_HUMAN Homo sapiens Beta-nerve growth factor