PDB 4edw

PDB Links
Overview

PDB Information

PDB	4EDW
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes. La Porte, S.L., Eigenbrot, C., Ultsch, M., Ho, W.H., Foletti, D., Forgie, A., Lindquist, K.C., Shelton, D.L., Pons, J. MAbs
Header	Immune System
Released	2012-03-27
Resolution	2.480
CATH Insert Date	06 Apr, 2014

PDB Images (9)

Image of CATH 4edw

4edw

PDB 4edw

Image of CATH 4edwH

4edwH

PDB Chain 4edwH

Image of CATH 4edwL

4edwL

PDB Chain 4edwL

Image of CATH 4edwV

4edwV

PDB Chain 4edwV

Image of CATH 4edwH01

4edwH01

CATH Domain 4edwH01

Image of CATH 4edwH02

4edwH02

CATH Domain 4edwH02

Image of CATH 4edwL01

4edwL01

CATH Domain 4edwL01

Image of CATH 4edwL02

4edwL02

CATH Domain 4edwL02

Image of CATH 4edwV00

4edwV00

CATH Domain 4edwV00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
H	07 Apr, 2014	Chopped
L	07 Apr, 2014	Chopped
V	07 Apr, 2014	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4edwH01	17 Apr, 2014	2.60.40.10	Assigned
4edwH02	17 Apr, 2014	2.60.40.10	Assigned
4edwL01	25 Apr, 2014	2.60.40.10	Assigned
4edwL02	25 Apr, 2014	2.60.40.10	Assigned
4edwV00	17 Apr, 2014	2.10.90.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P01138	NGF_HUMAN	Homo sapiens	Beta-nerve growth factor