PDB 4dwk

PDB Links
Overview

PDB Information

PDB	4DWK
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	Homo sapiens
Primary Citation	Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis. Charton, J., Gauriot, M., Guo, Q., Hennuyer, N., Marechal, X., Dumont, J., Hamdane, M., Pottiez, V., Landry, V., Sperandio, O., Flipo, M., Buee, L., Staels, B., Leroux, F., Tang, W.J., Deprez, B., Deprez-Poulain, R. Eur.J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2012-02-24
Resolution	3.000
CATH Insert Date	07 Jul, 2013

PDB Images (11)

Image of CATH 4dwk

4dwk

PDB 4dwk

Image of CATH 4dwkA

4dwkA

PDB Chain 4dwkA

Image of CATH 4dwkB

4dwkB

PDB Chain 4dwkB

Image of CATH 4dwkA01

4dwkA01

CATH Domain 4dwkA01

Image of CATH 4dwkA02

4dwkA02

CATH Domain 4dwkA02

Image of CATH 4dwkA03

4dwkA03

CATH Domain 4dwkA03

Image of CATH 4dwkA04

4dwkA04

CATH Domain 4dwkA04

Image of CATH 4dwkB01

4dwkB01

CATH Domain 4dwkB01

Image of CATH 4dwkB02

4dwkB02

CATH Domain 4dwkB02

Image of CATH 4dwkB03

4dwkB03

CATH Domain 4dwkB03

Image of CATH 4dwkB04

4dwkB04

CATH Domain 4dwkB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	08 Jul, 2013	Chopped
B	08 Jul, 2013	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4dwkA01	31 Aug, 2013	3.30.830.10	Assigned
4dwkA02	31 Aug, 2013	3.30.830.10	Assigned
4dwkA03	31 Aug, 2013	3.30.830.10	Assigned
4dwkA04	31 Aug, 2013	3.30.830.10	Assigned
4dwkB01	31 Aug, 2013	3.30.830.10	Assigned
4dwkB02	31 Aug, 2013	3.30.830.10	Assigned
4dwkB03	31 Aug, 2013	3.30.830.10	Assigned
4dwkB04	31 Aug, 2013	3.30.830.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme