PDB 4dbs

PDB Information

PDB4DBS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Crystal structures of AKR1C3 containing an N-(aryl)amino-benzoate inhibitor and a bifunctional AKR1C3 inhibitor and androgen receptor antagonist. Therapeutic leads for castrate resistant prostate cancer.
Chen, M., Adeniji, A.O., Twenter, B.M., Winkler, J.D., Christianson, D.W., Penning, T.M.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2012-01-16
Resolution1.850
CATH Insert Date27 May, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4dbsA00 08 Jun, 2012 3.20.20.100 Assigned
4dbsB00 08 Jun, 2012 3.20.20.100 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P42330 AK1C3_HUMAN Homo sapiens Aldo-keto reductase family 1 member C3
P42330 AK1C3_HUMAN Homo sapiens Aldo-keto reductase family 1 member C3