PDB 4d9r

PDB Information

PDB4D9R
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Inhibiting alternative pathway complement activation by targeting the factor d exosite.
Katschke, K.J., Wu, P., Ganesan, R., Kelley, R.F., Mathieu, M.A., Hass, P.E., Murray, J., Kirchhofer, D., Wiesmann, C., van Lookeren Campagne, M.
J.Biol.Chem.
HeaderHydrolase/Immune System
Released2012-01-11
Resolution2.420
CATH Insert Date26 Feb, 2012

PDB Images (19)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 27 Feb, 2012 Chopped
B 27 Feb, 2012 Chopped
D 27 Feb, 2012 Chopped
E 27 Feb, 2012 Chopped
H 27 Feb, 2012 Chopped
L 27 Feb, 2012 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
4d9rA01 08 Jun, 2012 2.40.10.10 Assigned
4d9rA02 08 Jun, 2012 2.40.10.10 Assigned
4d9rB01 08 Jun, 2012 2.40.10.10 Assigned
4d9rB02 08 Jun, 2012 2.40.10.10 Assigned
4d9rD01 08 Jun, 2012 2.60.40.10 Assigned
4d9rD02 08 Jun, 2012 2.60.40.10 Assigned
4d9rE01 08 Jun, 2012 2.60.40.10 Assigned
4d9rE02 08 Jun, 2012 2.60.40.10 Assigned
4d9rH01 08 Jun, 2012 2.60.40.10 Assigned
4d9rH02 08 Jun, 2012 2.60.40.10 Assigned
4d9rL01 08 Jun, 2012 2.60.40.10 Assigned
4d9rL02 08 Jun, 2012 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D