PDB 4d2w

PDB Links
Overview

PDB Information

PDB	4D2W
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase Johnson, C.N., Berdini, V., Beke, L., Bonnet, P., Brehmer, D., Coyle, J.E., Day, P.J., Frederickson, M., Freyne, E.J.E., Gilissen, R.A.H.J., Hamlett, C.C.F., Howard, S., Meerpoel, L., Mcmenamin, R., Patel, S., Rees, D.C., Sharff, A., Sommen, F., Wu, T., Linders, J.T.M. Acs Med.Chem.Lett.
Header	Transferase
Released	2014-05-13
Resolution	1.920
CATH Insert Date	19 Oct, 2014

PDB Images (9)

Image of CATH 4d2w

4d2w

PDB 4d2w

Image of CATH 4d2wA

4d2wA

PDB Chain 4d2wA

Image of CATH 4d2wB

4d2wB

PDB Chain 4d2wB

Image of CATH 4d2wC

4d2wC

PDB Chain 4d2wC

Image of CATH 4d2wD

4d2wD

PDB Chain 4d2wD

Image of CATH 4d2wA00

4d2wA00

CATH Domain 4d2wA00

Image of CATH 4d2wB00

4d2wB00

CATH Domain 4d2wB00

Image of CATH 4d2wC00

4d2wC00

CATH Domain 4d2wC00

Image of CATH 4d2wD00

4d2wD00

CATH Domain 4d2wD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	20 Oct, 2014	Chopped
B	20 Oct, 2014	Chopped
C	20 Oct, 2014	Chopped
D	20 Oct, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4d2wA00	21 Oct, 2014	1.10.510.10	Assigned
4d2wB00	21 Oct, 2014	1.10.510.10	Assigned
4d2wC00	21 Oct, 2014	1.10.510.10	Assigned
4d2wD00	21 Oct, 2014	1.10.510.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q14680	MELK_HUMAN	Homo sapiens	Maternal embryonic leucine zipper kinase
Q14680	MELK_HUMAN	Homo sapiens	Maternal embryonic leucine zipper kinase
Q14680	MELK_HUMAN	Homo sapiens	Maternal embryonic leucine zipper kinase
Q14680	MELK_HUMAN	Homo sapiens	Maternal embryonic leucine zipper kinase