PDB Information

PDB4CYU
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceSTAPHYLOCOCCUS AUREUS
Primary Citation
Structure-Based Design and Development of Functionalized Mercaptoguanine Derivatives as Inhibitors of the Folate Biosynthesis Pathway Enzyme 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase from Staphylococcus Aureus.
Dennis, M.L., Chhabra, S., Wang, Z., Debono, A., Dolezal, O., Newman, J., Pitcher, N.P., Rahmani, R., Cleary, B., Barlow, N., Hattarki, M., Graham, B., Peat, T.S., Baell, J.B., Swarbrick, J.D.
J.Med.Chem.
HeaderTransferase
Released2014-04-15
Resolution2.700
CATH Insert Date28 Jun, 2015

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4cyuA00 10 Jul, 2015 3.30.70.560 Assigned
4cyuB00 10 Jul, 2015 3.30.70.560 Assigned
4cyuC00 10 Jul, 2015 3.30.70.560 Assigned
4cyuD00 10 Jul, 2015 3.30.70.560 Assigned

UniProtKB Entries (0)

Accession Gene ID Taxon Description