PDB 4cmh

PDB Links
Overview

PDB Information

PDB	4CMH
Method	X-RAY DIFFRACTION
Host Organism	Homo sapiens
Gene Source	Homo sapiens
Primary Citation	SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies. Deckert, J., Wetzel, M.C., Bartle, L.M., Skaletskaya, A., Goldmacher, V.S., Vallee, F., Zhou-Liu, Q., Ferrari, P., Pouzieux, S., Lahoute, C., Dumontet, C., Plesa, A., Chiron, M., Lejeune, P., Chittenden, T., Park, P.U., Blanc, V. Clin. Cancer Res.
Header	Hydrolase/Immune System
Released	2014-01-15
Resolution	1.530
CATH Insert Date	27 Jul, 2014

PDB Images (10)

Image of CATH 4cmh

4cmh

PDB 4cmh

Image of CATH 4cmhA

4cmhA

PDB Chain 4cmhA

Image of CATH 4cmhB

4cmhB

PDB Chain 4cmhB

Image of CATH 4cmhC

4cmhC

PDB Chain 4cmhC

Image of CATH 4cmhA01

4cmhA01

CATH Domain 4cmhA01

Image of CATH 4cmhA02

4cmhA02

CATH Domain 4cmhA02

Image of CATH 4cmhB01

4cmhB01

CATH Domain 4cmhB01

Image of CATH 4cmhB02

4cmhB02

CATH Domain 4cmhB02

Image of CATH 4cmhC01

4cmhC01

CATH Domain 4cmhC01

Image of CATH 4cmhC02

4cmhC02

CATH Domain 4cmhC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	28 Jul, 2014	Chopped
B	28 Jul, 2014	Chopped
C	28 Jul, 2014	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4cmhA01	03 Aug, 2014	1.20.82.10	Assigned
4cmhA02	03 Aug, 2014	3.40.50.720	Assigned
4cmhB01	03 Aug, 2014	2.60.40.10	Assigned
4cmhB02	03 Aug, 2014	2.60.40.10	Assigned
4cmhC01	03 Aug, 2014	2.60.40.10	Assigned
4cmhC02	03 Aug, 2014	2.60.40.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P28907	CD38_HUMAN	Homo sapiens	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1