PDB Information

Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies.
Deckert, J., Wetzel, M.C., Bartle, L.M., Skaletskaya, A., Goldmacher, V.S., Vallee, F., Zhou-Liu, Q., Ferrari, P., Pouzieux, S., Lahoute, C., Dumontet, C., Plesa, A., Chiron, M., Lejeune, P., Chittenden, T., Park, P.U., Blanc, V.
Clin. Cancer Res.
HeaderHydrolase/Immune System
CATH Insert Date27 Jul, 2014

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 28 Jul, 2014 Chopped
B 28 Jul, 2014 Chopped
C 28 Jul, 2014 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4cmhA01 03 Aug, 2014 Assigned
4cmhA02 03 Aug, 2014 Assigned
4cmhB01 03 Aug, 2014 Assigned
4cmhB02 03 Aug, 2014 Assigned
4cmhC01 03 Aug, 2014 Assigned
4cmhC02 03 Aug, 2014 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P28907 CD38_HUMAN Homo sapiens ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1