PDB 4cku

PDB Information

PDB4CKU
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourcePLASMODIUM FALCIPARUM
Primary Citation
Plasmepsin Inhibitory Activity and Structure-Guided Optimization of a Potent Hydroxyethylamine-Based Antimalarial Hit.
Jaudzems, K., Tars, K., Maurops, G., Ivdra, N., Otikovs, M., Leitans, J., Kanepe-Lapsa, I., Domraceva, I., Mutule, I., Trapencieris, P., Blackman, M.J., Jirgensons, A.
Acs Med.Chem.Lett.
HeaderHydrolase
Released2014-01-08
Resolution1.850
CATH Insert Date29 Jun, 2014

PDB Images (19)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 30 Jun, 2014 Chopped
B 30 Jun, 2014 Chopped
C 30 Jun, 2014 Chopped
D 30 Jun, 2014 Chopped
E 30 Jun, 2014 Chopped
F 30 Jun, 2014 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
4ckuA01 03 Jul, 2014 2.40.70.10 Assigned
4ckuA02 03 Jul, 2014 2.40.70.10 Assigned
4ckuB01 03 Jul, 2014 2.40.70.10 Assigned
4ckuB02 03 Jul, 2014 2.40.70.10 Assigned
4ckuC01 03 Jul, 2014 2.40.70.10 Assigned
4ckuC02 03 Jul, 2014 2.40.70.10 Assigned
4ckuD01 03 Jul, 2014 2.40.70.10 Assigned
4ckuD02 03 Jul, 2014 2.40.70.10 Assigned
4ckuE01 03 Jul, 2014 2.40.70.10 Assigned
4ckuE02 03 Jul, 2014 2.40.70.10 Assigned
4ckuF01 02 Jul, 2014 2.40.70.10 Assigned
4ckuF02 02 Jul, 2014 2.40.70.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P46925 PLM2_PLAFA Plasmodium falciparum Plasmepsin-2
P46925 PLM2_PLAFA Plasmodium falciparum Plasmepsin-2
P46925 PLM2_PLAFA Plasmodium falciparum Plasmepsin-2
P46925 PLM2_PLAFA Plasmodium falciparum Plasmepsin-2
P46925 PLM2_PLAFA Plasmodium falciparum Plasmepsin-2
P46925 PLM2_PLAFA Plasmodium falciparum Plasmepsin-2