PDB 4cfw

PDB Information

PDB4CFW
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI B
Gene SourceHOMO SAPIENS
Primary Citation
8-Substituted O6-Cyclohexylmethylguanine Cdk2 Inhibitors; Using Structure-Based Inhibitor Design to Optimise an Alternative Binding Mode.
Carbain, B., Paterson, D.J., Anscombe, E., Campbell-Dexter, A., Cano, C., Echalier, A., Endicott, J., Golding, B.T., Haggerty, K., Hardcastle, I.R., Jewsbury, P.J., Newell, D.R., Noble, M., Roche, C., Wang, L., Griffin, R.J.
J.Med.Chem.
HeaderCell Cycle
Released2013-11-19
Resolution2.450
CATH Insert Date22 Dec, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 23 Dec, 2013 Chopped
B 23 Dec, 2013 Chopped
C 23 Dec, 2013 Chopped
D 23 Dec, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4cfwA01 26 Dec, 2013 3.30.200.20 Assigned
4cfwA02 26 Dec, 2013 1.10.510.10 Assigned
4cfwB01 26 Dec, 2013 1.10.472.10 Assigned
4cfwB02 26 Dec, 2013 1.10.472.10 Assigned
4cfwC01 26 Dec, 2013 3.30.200.20 Assigned
4cfwC02 26 Dec, 2013 1.10.510.10 Assigned
4cfwD01 26 Dec, 2013 1.10.472.10 Assigned
4cfwD02 26 Dec, 2013 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2