PDB 4cfv

PDB Information

PDB4CFV
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI B
Gene SourceHOMO SAPIENS
Primary Citation
8-Substituted O6-Cyclohexylmethylguanine Cdk2 Inhibitors; Using Structure-Based Inhibitor Design to Optimise an Alternative Binding Mode.
Carbain, B., Paterson, D.J., Anscombe, E., Campbell-Dexter, A., Cano, C., Echalier, A., Endicott, J., Golding, B.T., Haggerty, K., Hardcastle, I.R., Jewsbury, P.J., Newell, D.R., Noble, M., Roche, C., Wang, L., Griffin, R.J.
J.Med.Chem.
HeaderTransferase
Released2013-11-19
Resolution2.000
CATH Insert Date21 Dec, 2014

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 22 Dec, 2014 Chopped
B 22 Dec, 2014 Chopped
C 22 Dec, 2014 Chopped
D 22 Dec, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4cfvA01 29 Dec, 2014 3.30.200.20 Assigned
4cfvA02 29 Dec, 2014 1.10.510.10 Assigned
4cfvB01 29 Dec, 2014 1.10.472.10 Assigned
4cfvB02 29 Dec, 2014 1.10.472.10 Assigned
4cfvC01 29 Dec, 2014 3.30.200.20 Assigned
4cfvC02 29 Dec, 2014 1.10.510.10 Assigned
4cfvD01 29 Dec, 2014 1.10.472.10 Assigned
4cfvD02 29 Dec, 2014 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2