PDB 4cfu

PDB Information

PDB4CFU
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI B
Gene SourceHOMO SAPIENS
Primary Citation
8-Substituted O6-Cyclohexylmethylguanine Cdk2 Inhibitors; Using Structure-Based Inhibitor Design to Optimise an Alternative Binding Mode.
Carbain, B., Paterson, D.J., Anscombe, E., Campbell-Dexter, A., Cano, C., Echalier, A., Endicott, J., Golding, B.T., Haggerty, K., Hardcastle, I.R., Jewsbury, P.J., Newell, D.R., Noble, M., Roche, C., Wang, L., Griffin, R.J.
J.Med.Chem.
HeaderTransferase
Released2013-11-19
Resolution2.200
CATH Insert Date21 Dec, 2014

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 22 Dec, 2014 Chopped
B 22 Dec, 2014 Chopped
C 22 Dec, 2014 Chopped
D 22 Dec, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4cfuA01 29 Dec, 2014 3.30.200.20 Assigned
4cfuA02 29 Dec, 2014 1.10.510.10 Assigned
4cfuB01 29 Dec, 2014 1.10.472.10 Assigned
4cfuB02 29 Dec, 2014 1.10.472.10 Assigned
4cfuC01 29 Dec, 2014 3.30.200.20 Assigned
4cfuC02 29 Dec, 2014 1.10.510.10 Assigned
4cfuD01 29 Dec, 2014 1.10.472.10 Assigned
4cfuD02 29 Dec, 2014 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2