PDB 4cfm

PDB Information

PDB4CFM
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI B
Gene SourceHOMO SAPIENS
Primary Citation
8-Substituted O6-Cyclohexylmethylguanine Cdk2 Inhibitors; Using Structure-Based Inhibitor Design to Optimise an Alternative Binding Mode.
Carbain, B., Paterson, D.J., Anscombe, E., Campbell-Dexter, A., Cano, C., Echalier, A., Endicott, J., Golding, B.T., Haggerty, K., Hardcastle, I.R., Jewsbury, P.J., Newell, D.R., Noble, M., Roche, C., Wang, L., Griffin, R.J.
J.Med.Chem.
HeaderCell Cycle
Released2013-11-18
Resolution2.850
CATH Insert Date21 Dec, 2014

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 22 Dec, 2014 Chopped
B 22 Dec, 2014 Chopped
C 22 Dec, 2014 Chopped
D 22 Dec, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4cfmA01 28 Dec, 2014 3.30.200.20 Assigned
4cfmA02 28 Dec, 2014 1.10.510.10 Assigned
4cfmB01 28 Dec, 2014 1.10.472.10 Assigned
4cfmB02 28 Dec, 2014 1.10.472.10 Assigned
4cfmC01 28 Dec, 2014 3.30.200.20 Assigned
4cfmC02 28 Dec, 2014 1.10.510.10 Assigned
4cfmD01 28 Dec, 2014 1.10.472.10 Assigned
4cfmD02 28 Dec, 2014 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2