PDB Information

PDB4BVE
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Ex-527 Inhibits Sirtuins by Exploiting Their Unique Nad+-Dependent Deacetylation Mechanism
Gertz, M., Fischer, F., Nguyen, G.T.T., Lakshminarasimhan, M., Schutkowski, M., Weyand, M., Steegborn, C.
Proc.Natl.Acad.Sci.USA
HeaderHydrolase/Ligase
Released2013-06-25
Resolution2.050
CATH Insert Date04 Aug, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Aug, 2013 Chopped
B 05 Aug, 2013 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4bveA01 14 Aug, 2013 3.40.50.1220 Assigned
4bveA02 14 Aug, 2013 3.30.1600.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9NUB1 ACS2L_HUMAN Homo sapiens Acetyl-coenzyme A synthetase 2-like, mitochondrial
Q9NTG7 SIR3_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-3, mitochondrial