PDB Information

PDB4BUZ
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceTHERMOTOGA MARITIMA
Primary Citation
Ex-527 Inhibits Sirtuins by Exploiting Their Unique Nad+-Dependent Deacetylation Mechanism
Gertz, M., Fischer, F., Nguyen, G.T.T., Lakshminarasimhan, M., Schutkowski, M., Weyand, M., Steegborn, C.
Proc.Natl.Acad.Sci.USA
HeaderHydrolase
Released2013-06-24
Resolution1.900
CATH Insert Date04 Aug, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Aug, 2013 Chopped
P 05 Aug, 2013 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4buzA01 26 Oct, 2013 3.40.50.1220 Assigned
4buzA02 26 Oct, 2013 3.30.1600.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04637 P53_HUMAN Homo sapiens Cellular tumor antigen p53
Q9WYW0 NPD_THEMA Thermotoga maritima MSB8 NAD-dependent protein deacetylase