PDB 4b9k

PDB Information

PDB4B9K
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1 Alpha
Buckley, D.L., Gustafson, J.L., Van Molle, I., Roth, A.G., Tae, H.S., Gareiss, P.C., Jorgensen, W.L., Ciulli, A., Crews, C.M.
Angew.Chem.Int.Ed.Engl.
HeaderLigase
Released2012-09-05
Resolution2.000
CATH Insert Date04 Nov, 2012

PDB Images (29)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped
C 05 Nov, 2012 Chopped
D 05 Nov, 2012 Chopped
E 05 Nov, 2012 Chopped
F 05 Nov, 2012 Chopped
G 05 Nov, 2012 Chopped
H 05 Nov, 2012 Chopped
I 05 Nov, 2012 Chopped
J 05 Nov, 2012 Chopped
K 05 Nov, 2012 Chopped
L 05 Nov, 2012 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
4b9kA00 10 Nov, 2012 3.10.20.90 Assigned
4b9kB00 10 Nov, 2012 3.30.710.10 Assigned
4b9kC01 10 Nov, 2012 2.60.40.780 Assigned
4b9kC02 10 Nov, 2012 1.10.750.10 Assigned
4b9kD00 10 Nov, 2012 3.10.20.90 Assigned
4b9kE00 10 Nov, 2012 3.30.710.10 Assigned
4b9kF01 10 Nov, 2012 2.60.40.780 Assigned
4b9kF02 10 Nov, 2012 1.10.750.10 Assigned
4b9kG00 10 Nov, 2012 3.10.20.90 Assigned
4b9kH00 10 Nov, 2012 3.30.710.10 Assigned
4b9kI01 10 Nov, 2012 2.60.40.780 Assigned
4b9kI02 10 Nov, 2012 1.10.750.10 Assigned
4b9kJ00 10 Nov, 2012 3.10.20.90 Assigned
4b9kK00 10 Nov, 2012 3.30.710.10 Assigned
4b9kL01 10 Nov, 2012 2.60.40.780 Assigned
4b9kL02 10 Nov, 2012 1.10.750.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15369 ELOC_HUMAN Homo sapiens Elongin-C