PDB 4ajh

PDB Information

PDB4AJH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceRattus norvegicus
Primary Citation
The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation
Ward, R., Brassington, C., Breeze, A.L., Caputo, A., Critchlow, S., Davies, G., Goodwin, L., Hassall, G., Greenwood, R., Holdgate, G., Mrosek, M., Norman, R.A., Pearson, S., Tart, J., Tucker, J.A., Vogtherr, M., Whittaker, D., Wingfield, J., Winter, J., Hudson, K.
J.Med.Chem.
HeaderOxidoreductase/Inhibitor
Released2012-02-16
Resolution1.930
CATH Insert Date27 May, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4ajhA01 01 Feb, 2013 3.40.50.720 Assigned
4ajhA02 01 Feb, 2013 3.90.110.10 Assigned
4ajhB01 01 Feb, 2013 3.40.50.720 Assigned
4ajhB02 01 Feb, 2013 3.90.110.10 Assigned
4ajhC01 01 Feb, 2013 3.40.50.720 Assigned
4ajhC02 01 Feb, 2013 3.90.110.10 Assigned
4ajhD01 01 Feb, 2013 3.40.50.720 Assigned
4ajhD02 01 Feb, 2013 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain