PDB 4aje

PDB Information

PDB4AJE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceRattus norvegicus
Primary Citation
The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation
Ward, R., Brassington, C., Breeze, A.L., Caputo, A., Critchlow, S., Davies, G., Goodwin, L., Hassall, G., Greenwood, R., Holdgate, G., Mrosek, M., Norman, R.A., Pearson, S., Tart, J., Tucker, J.A., Vogtherr, M., Whittaker, D., Wingfield, J., Winter, J., Hudson, K.
J.Med.Chem.
HeaderOxidoreductase/Inhibitor
Released2012-02-16
Resolution2.350
CATH Insert Date27 May, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4ajeA01 01 Feb, 2013 3.40.50.720 Assigned
4ajeA02 01 Feb, 2013 3.90.110.10 Assigned
4ajeB01 01 Feb, 2013 3.40.50.720 Assigned
4ajeB02 01 Feb, 2013 3.90.110.10 Assigned
4ajeC01 01 Feb, 2013 3.40.50.720 Assigned
4ajeC02 01 Feb, 2013 3.90.110.10 Assigned
4ajeD01 01 Feb, 2013 3.40.50.720 Assigned
4ajeD02 01 Feb, 2013 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain