PDB 4agw

PDB Links
Overview

PDB Information

PDB	4AGW
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	GALLUS GALLUS
Primary Citation	Discovery of a Small-Molecule Type II Inhibitor of Wild-Type and Gatekeeper Mutants of Bcr-Abl, Pdgfralpha, Kit, and Src Kinases: Novel Type II Inhibitor of Gatekeeper Mutants. Weisberg, E., Choi, H.G., Ray, A., Barrett, R., Zhang, J., Sim, T., Zhou, W., Seeliger, M., Cameron, M., Azam, M., Fletcher, J.A., Debiec-Rychter, M., Mayeda, M., Moreno, D., Kung, A.L., Janne, P.A., Khosravi-Far, R., Melo, J.V., Manley, P.W., Adamia, S., Wu, C., Gray, N., Griffin, J.D. Blood
Header	Transferase
Released	2012-02-01
Resolution	2.600
CATH Insert Date	19 Feb, 2012

PDB Images (7)

Image of CATH 4agw

4agw

PDB 4agw

Image of CATH 4agwA

4agwA

PDB Chain 4agwA

Image of CATH 4agwB

4agwB

PDB Chain 4agwB

Image of CATH 4agwA01

4agwA01

CATH Domain 4agwA01

Image of CATH 4agwA02

4agwA02

CATH Domain 4agwA02

Image of CATH 4agwB01

4agwB01

CATH Domain 4agwB01

Image of CATH 4agwB02

4agwB02

CATH Domain 4agwB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	20 Feb, 2012	Chopped
B	20 Feb, 2012	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4agwA01	22 Feb, 2012	3.30.200.20	Assigned
4agwA02	22 Feb, 2012	1.10.510.10	Assigned
4agwB01	22 Feb, 2012	3.30.200.20	Assigned
4agwB02	22 Feb, 2012	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P00523	SRC_CHICK	Gallus gallus	Proto-oncogene tyrosine-protein kinase Src
P00523	SRC_CHICK	Gallus gallus	Proto-oncogene tyrosine-protein kinase Src