PDB Information

PDB4A9O
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Fragment-Based Discovery of Bromodomain Inhibitors Part 2: Optimization of Phenylisoxazole Sulfonamides.
Bamborough, P., Diallo, H., Goodacre, J.D., Gordon, L., Lewis, A., Seal, J.T., Wilson, D.M., Woodrow, M.D., Chung, C.W.
J.Med.Chem.
HeaderSignaling Protein/Inhibitor
Released2011-11-26
Resolution1.780
CATH Insert Date12 Feb, 2012

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 13 Feb, 2012 Chopped
B 13 Feb, 2012 Chopped
C 13 Feb, 2012 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4a9oA00 16 Feb, 2012 1.20.920.10 Assigned
4a9oB00 15 Feb, 2012 1.20.920.10 Assigned
4a9oC00 16 Feb, 2012 1.20.920.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2