PDB 3zlq

PDB Links
Overview

PDB Information

PDB	3ZLQ
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Beta-Secretase (Bace1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer'S Disease. Hilpert, H., Guba, W., Woltering, T.J., Wostl, W., Pinard, E., Mauser, H., Mayweg, A.V., Rogers-Evans, M., Humm, R., Krummenacher, D., Muser, T., Schnider, C., Jacobsen, H., Ozmen, L., Bergadano, A., Banner, D.W., Hochstrasser, R., Kuglstatter, A., David-Pierson, P., Fischer, H., Polara, A., Narquizian, R. J.Med.Chem.
Header	Hydrolase/Immune System
Released	2013-02-04
Resolution	2.100
CATH Insert Date	07 Jul, 2013

PDB Images (11)

Image of CATH 3zlq

3zlq

PDB 3zlq

Image of CATH 3zlqA

3zlqA

PDB Chain 3zlqA

Image of CATH 3zlqB

3zlqB

PDB Chain 3zlqB

Image of CATH 3zlqC

3zlqC

PDB Chain 3zlqC

Image of CATH 3zlqD

3zlqD

PDB Chain 3zlqD

Image of CATH 3zlqA01

3zlqA01

CATH Domain 3zlqA01

Image of CATH 3zlqA02

3zlqA02

CATH Domain 3zlqA02

Image of CATH 3zlqB01

3zlqB01

CATH Domain 3zlqB01

Image of CATH 3zlqB02

3zlqB02

CATH Domain 3zlqB02

Image of CATH 3zlqC00

3zlqC00

CATH Domain 3zlqC00

Image of CATH 3zlqD00

3zlqD00

CATH Domain 3zlqD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	08 Jul, 2013	Chopped
B	08 Jul, 2013	Chopped
C	08 Jul, 2013	Chopped
D	08 Jul, 2013	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3zlqA01	09 Aug, 2013	2.40.70.10	Assigned
3zlqA02	09 Aug, 2013	2.40.70.10	Assigned
3zlqB01	09 Aug, 2013	2.40.70.10	Assigned
3zlqB02	09 Aug, 2013	2.40.70.10	Assigned
3zlqC00	09 Aug, 2013	2.60.40.10	Assigned
3zlqD00	09 Aug, 2013	2.60.40.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y5Z0	BACE2_HUMAN	Homo sapiens	Beta-secretase 2
Q9Y5Z0	BACE2_HUMAN	Homo sapiens	Beta-secretase 2