PDB 3wv1

PDB Information

PDB3WV1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of novel, highly potent, and selective quinazoline-2-carboxamide-based matrix metalloproteinase (MMP)-13 inhibitors without a zinc binding group using a structure-based design approach
Nara, H., Sato, K., Naito, T., Mototani, H., Oki, H., Yamamoto, Y., Kuno, H., Santou, T., Kanzaki, N., Terauchi, J., Uchikawa, O., Kori, M.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-05-12
Resolution1.980
CATH Insert Date28 Jun, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3wv1A00 10 Jul, 2015 3.40.390.10 Assigned
3wv1B00 09 Jul, 2015 3.40.390.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P45452 MMP13_HUMAN Homo sapiens Collagenase 3
P45452 MMP13_HUMAN Homo sapiens Collagenase 3