PDB 3ws8

PDB Information

PDB3WS8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Novel benzimidazole derivatives as phosphodiesterase 10A (PDE10A) inhibitors with improved metabolic stability.
Chino, A., Masuda, N., Amano, Y., Honbou, K., Mihara, T., Yamazaki, M., Tomishima, M.
Bioorg.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-03-04
Resolution2.600
CATH Insert Date15 Jun, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Jun, 2014 Chopped
B 16 Jun, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3ws8A00 18 Jun, 2014 1.10.1300.10 Assigned
3ws8B00 18 Jun, 2014 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A