PDB 3wiy

PDB Information

PDB3WIY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins.
Tanaka, Y., Aikawa, K., Nishida, G., Homma, M., Sogabe, S., Igaki, S., Hayano, Y., Sameshima, T., Miyahisa, I., Kawamoto, T., Tawada, M., Imai, Y., Inazuka, M., Cho, N., Imaeda, Y., Ishikawa, T.
J.Med.Chem.
HeaderApoptosis
Released2013-09-26
Resolution2.150
CATH Insert Date01 Dec, 2013

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 02 Dec, 2013 Chopped
B 02 Dec, 2013 Chopped
C 02 Dec, 2013 Chopped
D 02 Dec, 2013 Chopped
E 02 Dec, 2013 Chopped
F 02 Dec, 2013 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
3wiyA01 04 Dec, 2013 1.10.437.10 Assigned
3wiyB01 04 Dec, 2013 1.10.437.10 Assigned
3wiyC01 04 Dec, 2013 1.10.437.10 Assigned
3wiyD01 04 Dec, 2013 1.10.437.10 Assigned
3wiyE01 04 Dec, 2013 1.10.437.10 Assigned
3wiyF01 04 Dec, 2013 1.10.437.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1