PDB 3wig

PDB Information

PDB3WIG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Disruption of CRAF-Mediated MEK Activation Is Required for Effective MEK Inhibition in KRAS Mutant Tumors
Lito, P., Saborowski, A., Yue, J., Solomon, M., Joseph, E., Gadal, S., Saborowski, M., Kastenhuber, E., Fellmann, C., Ohara, K., Morikami, K., Miura, T., Lukacs, C., Ishii, N., Lowe, S., Rosen, N.
Cancer Cell
HeaderTransferase/Transferase Inhibitor
Released2013-09-12
Resolution2.700
CATH Insert Date15 Jun, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Jun, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3wigA01 18 Jun, 2014 3.30.200.20 Assigned
3wigA02 18 Jun, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q02750 MP2K1_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1