PDB 3wgw

PDB Information

PDB3WGW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin.
Inoue, A., Kikuchi, S., Hishiki, A., Shao, Y., Heath, R., Evison, B.J., Actis, M., Canman, C.E., Hashimoto, H., Fujii, N.
J.Biol.Chem.
HeaderDna Binding Protein/Inhibitor
Released2013-08-12
Resolution2.800
CATH Insert Date09 Feb, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Feb, 2014 Chopped
B 10 Feb, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3wgwA00 07 Mar, 2014 3.70.10.10 Assigned
3wgwB00 07 Mar, 2014 3.70.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P12004 PCNA_HUMAN Homo sapiens Proliferating cell nuclear antigen
P12004 PCNA_HUMAN Homo sapiens Proliferating cell nuclear antigen