PDB 3vfa
PDB Information
PDB | 3VFA |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Human immunodeficiency virus type 1 lw12.3 isolate |
Primary Citation | Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring.
J.Med.Chem.
|
Header | Hydrolase/Hydrolase Inhibitor |
Released | 2012-01-09 |
Resolution | 1.430 |
CATH Insert Date | 02 Dec, 2012 |
PDB Images (5)
PDB Prints
PDB Chains (2)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 31 Dec, 2012 | Chopped |
B | 31 Dec, 2012 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
3vfaA00 | 03 Jan, 2013 | 2.40.70.10 | Assigned |
3vfaB00 | 02 Jan, 2013 | 2.40.70.10 | Assigned |
UniProtKB Entries (2)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P0C6F2 | POL_HV1LW | Human immunodeficiency virus type 1 lw12.3 isolate | Gag-Pol polyprotein |
P0C6F2 | POL_HV1LW | Human immunodeficiency virus type 1 lw12.3 isolate | Gag-Pol polyprotein |