PDB 3vf3

PDB Information

PDB3VF3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of cyclic sulfone hydroxyethylamines as potent and selective beta-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid beta-peptides
Rueeger, H., Lueoend, R., Rogel, O., Rondeau, J.M., Mobitz, H., Machauer, R., Jacobson, L., Staufenbiel, M., Desrayaud, S., Neumann, U.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-01-09
Resolution1.480
CATH Insert Date02 Dec, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 31 Dec, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3vf3A01 03 Jan, 2013 2.40.70.10 Assigned
3vf3A02 03 Jan, 2013 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1