Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections.
Montgomery, J.I., Brown, M.F., Reilly, U., Price, L.M., Abramite, J.A., Arcari, J., Barham, R., Che, Y., Chen, J.M., Chung, S.W., Collantes, E.M., Desbonnet, C., Doroski, M., Doty, J., Engtrakul, J.J., Harris, T.M., Huband, M., Knafels, J.D., Leach, K.L., Liu, S., Marfat, A., McAllister, L., McElroy, E., Menard, C.A., Mitton-Fry, M., Mullins, L., Noe, M.C., O'Donnell, J., Oliver, R., Penzien, J., Plummer, M., Shanmugasundaram, V., Thoma, C., Tomaras, A.P., Uccello, D.P., Vaz, A., Wishka, D.G.
J.Med.Chem.