PDB 3ufl

PDB Information

PDB3UFL
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Discovery of pyrrolidine-based beta-secretase inhibitors: Lead advancement through conformational design for maintenance of ligand binding efficiency.
Stachel, S.J., Steele, T.G., Petrocchi, A., Haugabook, S.J., McGaughey, G., Katharine Holloway, M., Allison, T., Munshi, S., Zuck, P., Colussi, D., Tugasheva, K., Wolfe, A., Graham, S.L., Vacca, J.P.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-11-01
Resolution1.900
CATH Insert Date22 Jan, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 23 Jan, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3uflA01 25 Jan, 2012 2.40.70.10 Assigned
3uflA02 25 Jan, 2012 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
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