PDB 3u6a

PDB Information

PDB3U6A
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Rational design and synthesis of aminopiperazinones as beta-secretase (BACE) inhibitors.
Tresadern, G., Delgado, F., Delgado, O., Gijsen, H., Macdonald, G.J., Moechars, D., Rombouts, F., Alexander, R., Spurlino, J., Van Gool, M., Vega, J.A., Trabanco, A.A.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-10-12
Resolution2.200
CATH Insert Date13 Nov, 2011

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped
B 29 Nov, 2011 Chopped
C 29 Nov, 2011 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
3u6aA01 01 Dec, 2011 2.40.70.10 Assigned
3u6aA02 01 Dec, 2011 2.40.70.10 Assigned
3u6aB01 01 Dec, 2011 2.40.70.10 Assigned
3u6aB02 01 Dec, 2011 2.40.70.10 Assigned
3u6aC01 01 Dec, 2011 2.40.70.10 Assigned
3u6aC02 01 Dec, 2011 2.40.70.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1