PDB Information

PDB3TYQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus
Primary Citation
A Novel Class of Highly Potent Irreversible Hepatitis C Virus NS5B Polymerase Inhibitors.
Chen, K.X., Lesburg, C.A., Vibulbhan, B., Yang, W., Chan, T.Y., Venkatraman, S., Velazquez, F., Zeng, Q., Bennett, F., Anilkumar, G.N., Duca, J., Jiang, Y., Pinto, P., Wang, L., Huang, Y., Selyutin, O., Gavalas, S., Pu, H., Agrawal, S., Feld, B., Huang, H.C., Li, C., Cheng, K.C., Shih, N.Y., Kozlowski, J.A., Rosenblum, S.B., Njoroge, F.G.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2011-09-26
Resolution1.600
CATH Insert Date05 Feb, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 06 Feb, 2012 Chopped
B 06 Feb, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3tyqA01 08 Oct, 2013 Holding pen
3tyqA02 08 Oct, 2013 Holding pen
3tyqB01 08 Oct, 2013 Holding pen
3tyqB02 08 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein