PDB 3tu7

PDB Information

PDB3TU7
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Molecular design and structure-activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664.
Das, J., Kimball, S.D., Hall, S.E., Han, W.C., Iwanowicz, E., Lin, J., Moquin, R.V., Reid, J.A., Sack, J.S., Malley, M.F., Chang, C.Y., Chong, S., Wang-Iverson, D.B., Roberts, D.G., Seiler, S.M., Schumacher, W.A., Ogletree, M.L.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-09-16
Resolution2.490
CATH Insert Date16 Oct, 2011

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 29 Nov, 2011 Chopped
I 29 Nov, 2011 Rejected
L 29 Nov, 2011 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3tu7H01 01 Dec, 2011 2.40.10.10 Assigned
3tu7H02 01 Dec, 2011 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P00734 THRB_HUMAN Homo sapiens Prothrombin
P09945 HIRV2_HIRME Hirudo medicinalis Hirudin variant-2
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