PDB 3tt0

PDB Links
Overview

PDB Information

PDB	3TT0
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase. Guagnano, V., Furet, P., Spanka, C., Bordas, V., Le Douget, M., Stamm, C., Brueggen, J., Jensen, M.R., Schnell, C., Schmid, H., Wartmann, M., Berghausen, J., Drueckes, P., Zimmerlin, A., Bussiere, D., Murray, J., Graus Porta, D. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2011-09-13
Resolution	2.800
CATH Insert Date	17 Jun, 2012

PDB Images (7)

Image of CATH 3tt0

3tt0

PDB 3tt0

Image of CATH 3tt0A

3tt0A

PDB Chain 3tt0A

Image of CATH 3tt0B

3tt0B

PDB Chain 3tt0B

Image of CATH 3tt0A01

3tt0A01

CATH Domain 3tt0A01

Image of CATH 3tt0A02

3tt0A02

CATH Domain 3tt0A02

Image of CATH 3tt0B01

3tt0B01

CATH Domain 3tt0B01

Image of CATH 3tt0B02

3tt0B02

CATH Domain 3tt0B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	18 Jun, 2012	Chopped
B	18 Jun, 2012	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3tt0A01	26 Jun, 2012	3.30.200.20	Assigned
3tt0A02	26 Jun, 2012	1.10.510.10	Assigned
3tt0B01	26 Jun, 2012	3.30.200.20	Assigned
3tt0B02	26 Jun, 2012	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P11362	FGFR1_HUMAN	Homo sapiens	Fibroblast growth factor receptor 1
P11362	FGFR1_HUMAN	Homo sapiens	Fibroblast growth factor receptor 1